Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses.

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses.

Lipid antigens trigger help from natural killer T cells (NKT cells) for B cells, and direct conjugation of lipid agonists to antigen profoundly augments antibody responses. Here we show that in vivo, NKT cells engaged in stable and prolonged cognate interactions with B cells and induced the formatio...

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Bibliographic Details
Main Authors: Chang, P, Barral, P, Fitch, J, Pratama, A, Ma, C, Kallies, A, Hogan, J, Cerundolo, V, Tangye, S, Bittman, R, Nutt, S, Brink, R, Godfrey, D, Batista, F, Vinuesa, C
Format: Journal article
Language:English
Published: 2012

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