The C-4 stereochemistry of leucocyanidin substrates for anthocyanidin synthase affects product selectivity.

The C-4 stereochemistry of leucocyanidin substrates for anthocyanidin synthase affects product selectivity.

Anthocyanidin synthase (ANS), an iron(II) and 2-oxoglutarate (2OG) dependent oxygenase, catalyses the penultimate step in anthocyanin biosynthesis by oxidation of the 2R,3S,4S-cis-leucoanthocyanidins. It has been believed that in vivo the products of ANS are the anthocyanidins. However, in vitro stu...

Full description

Bibliographic Details
Main Authors:	Turnbull, J, Nagle, M, Seibel, J, Welford, R, Grant, G, Schofield, C
Format:	Journal article
Language:	English
Published:	2003

Similar Items

Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism.
by: Welford, R, et al.
Published: (2005)

Are anthocyanidins the immediate products of anthocyanidin synthase?
by: Turnbull, J, et al.
Published: (2000)

Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana.
by: Wilmouth, R, et al.
Published: (2002)

Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase.
by: Turnbull, J, et al.
Published: (2004)

Purification, crystallization and preliminary X-ray diffraction of anthocyanidin synthase from Arabidopsis thaliana.
by: Turnbull, J, et al.
Published: (2001)

Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.
by: Lloyd, MD, et al.
Published: (2004)

Extraction, Bacteriostatic Effect and Synergistic Mechanism of Bacteriostatic Effect of Taxifolin in Larch in Combination with Leucocyanidin
by: Licheng JING, et al.
Published: (2024-01-01)

PENICILLIN BIOSYNTHESIS - DEPENDENCE OF SUBSTRATE STEREOCHEMISTRY ON THE MODE OF 2ND RING-CLOSURE
by: Baldwin, J, et al.
Published: (1990)

The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases
by: David H. Kwan, et al.
Published: (2011-07-01)

Function analysis of anthocyanidin synthase from Morus alba L. by expression in bacteria and tobacco
by: Jun Li, et al.
Published: (2018-11-01)

Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258.
by: Lee, H, et al.
Published: (2001)

Adipoyl-6-aminopenicillanic acid is a substrate for deacetoxycephalosporin C synthase (DAOCS)
by: Shibata, N, et al.
Published: (1996)

Oxidative Transformation of Dihydroflavonols and Flavan-3-ols by Anthocyanidin Synthase from <i>Vitis vinifera</i>
by: Jia-Rong Zhang, et al.
Published: (2022-02-01)

Nonsense mutation inside anthocyanidin synthase gene controls pigmentation in yellow raspberry (Rubus idaeus L.).
by: Muhammad Zubair Rafique, et al.
Published: (2016-12-01)

Symmetry and stereochemistry/
by: 423938 Donaldson, J., et al.
Published: (1972)

Stereochemistry /
by: Dhillon, Ranjit S., author, et al.
Published: (2014)

Stereochemistry/
by: Tamm, Ch
Published: (1982)

Stereochemistry /
by: 204228 Morris, David G., et al.
Published: (2002)

Stereochemistry /
by: Ramsay, O. Bertrand (Ogden Bertrand), 1932-
Published: (1981)

Stereochemistry /
by: 239693 Natta, Giulio, et al.
Published: (1972)

Geometric morphometrics reveals shifts in flower shape symmetry and size following gene knockdown of CYCLOIDEA and ANTHOCYANIDIN SYNTHASE
by: Brent A. Berger, et al.
Published: (2017-11-01)

The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase.
by: Lipscomb, S, et al.
Published: (2002)

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.
by: Welford, R, et al.
Published: (2001)

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.
by: Welford, R, et al.
Published: (2001)

Membrane permeability selection drove the stereochemistry of life
by: Goode, O, et al.
Published: (2024)

Stereochemistry and mechanism/
by: 228209 Whittaker, David
Published: (1973)

Topic in stereochemistry/
by: Allinger, Norman L., et al.
Published: (1967)

Organic stereochemistry/
by: 280021 Kagan, Henri
Published: (1979)

Supramolecular stereochemistry /
by: Siegel, Jay S
Published: (1995)

Guidebook to stereochemistry/
by: 445802 Gunstone, F. D.
Published: (1975)

Introduction to stereochemistry/
by: 239778 Mislow, Kurt
Published: (1965)

Organophosphorus stereochemistry/
by: McEwen, William E.
Published: (1975)

Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis (Sept, pg 1828, 2001)
by: Welford, R, et al.
Published: (2001)

SUBSTRATE-ANALOG STUDIES ON CLAVAMINIC ACID SYNTHASE
by: Baldwin, J, et al.
Published: (1993)

Erratum: Evidence for oxidation at c-3 of the flavonoid c-ring during anthocyanin biosynthesis (Chemical Communications (2001)(1828)
by: Welford, R, et al.
Published: (2001)

Stereochemistry and bonding in inorganic chemistry/
by: 243934 Fergusson, J. E.
Published: (1974)

On the absolute stereochemistry of pyrinodemin A.
by: Romeril, S, et al.
Published: (2003)

Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
by: Sleeman, M, et al.
Published: (2004)

Stereochemistry conformation and mechanism /
by: 295857 Kalsi, P.S
Published: (2003)

Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.
by: Dubus, A, et al.
Published: (2001)