Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank

<p>We aimed to identify potential novel predictors for breast cancer among post-menopausal women, with pre-specified interest in the role of polygenic risk scores (PRS) for risk prediction. We utilised an analysis pipeline where machine learning was used for feature selection, prior to risk pr...

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Hlavní autoři: Liu, X, Morelli, D, Littlejohns, TJ, Clifton, DA, Clifton, L
Médium: Journal article
Jazyk:English
Vydáno: Springer Nature 2023