Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

<p><strong>Background</strong></p> Doxycycline is often used for treating COVID-19 respiratory symptoms in the community despite an absence of evidence from clinical trials to support its use. We aimed to assess the efficacy of doxycycline to treat suspected COVID-19 in the c...

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Main Authors: Butler, CC, Yu, L-M, Dorward, J, Gbinigie, O, Hayward, G, Saville, BR, Van Hecke, O, Berry, N, Detry, MA, Saunders, C, Fitzgerald, M, Harris, V, Djukanovic, R, Gadola, S, Kirkpatrick, J, Ogburn, E, Patel, MG, de Lusignan, S, Evans, PH, Thomas, NPB, Hobbs, FDR
Other Authors: PRINCIPLE Trial Collaborative Group
Format: Journal article
Language:English
Published: Elsevier 2021

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