Arginine methylation regulates the p53 response.

Activation of the p53 tumour suppressor protein in response to DNA damage leads to apoptosis or cell-cycle arrest. Enzymatic modifications are widely believed to affect and regulate p53 activity. We describe here a level of post-translational control that has an important functional consequence on t...

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Bibliographic Details
Main Authors: Jansson, M, Durant, S, Cho, E, Sheahan, S, Edelmann, M, Kessler, B, La Thangue, N
Format: Journal article
Language:English
Published: 2008