X-ray studies on the mechanism of IPNS using substrate analogs
The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate...
وصف كامل
التفاصيل البيبلوغرافية
| المؤلفون الرئيسيون: |
Long, A,
Clifton, I,
Roach, P,
Schofield, C,
Baldwin, J,
Hajdu, J |
|---|
| التنسيق: | Journal article
|
|---|
| اللغة: | English |
|---|
| منشور في: |
1997
|
|---|