X-ray studies on the mechanism of IPNS using substrate analogs

The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate...

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Κύριοι συγγραφείς: Long, A, Clifton, I, Roach, P, Schofield, C, Baldwin, J, Hajdu, J
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 1997
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author Long, A
Clifton, I
Roach, P
Schofield, C
Baldwin, J
Hajdu, J
author_facet Long, A
Clifton, I
Roach, P
Schofield, C
Baldwin, J
Hajdu, J
author_sort Long, A
collection OXFORD
description The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate, L-8-(
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spelling oxford-uuid:615d0e21-d29d-4a61-906b-2dd2b826611a2022-03-26T17:59:23ZX-ray studies on the mechanism of IPNS using substrate analogsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:615d0e21-d29d-4a61-906b-2dd2b826611aEnglishSymplectic Elements at Oxford1997Long, AClifton, IRoach, PSchofield, CBaldwin, JHajdu, JThe substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate, L-8-(
spellingShingle Long, A
Clifton, I
Roach, P
Schofield, C
Baldwin, J
Hajdu, J
X-ray studies on the mechanism of IPNS using substrate analogs
title X-ray studies on the mechanism of IPNS using substrate analogs
title_full X-ray studies on the mechanism of IPNS using substrate analogs
title_fullStr X-ray studies on the mechanism of IPNS using substrate analogs
title_full_unstemmed X-ray studies on the mechanism of IPNS using substrate analogs
title_short X-ray studies on the mechanism of IPNS using substrate analogs
title_sort x ray studies on the mechanism of ipns using substrate analogs
work_keys_str_mv AT longa xraystudiesonthemechanismofipnsusingsubstrateanalogs
AT cliftoni xraystudiesonthemechanismofipnsusingsubstrateanalogs
AT roachp xraystudiesonthemechanismofipnsusingsubstrateanalogs
AT schofieldc xraystudiesonthemechanismofipnsusingsubstrateanalogs
AT baldwinj xraystudiesonthemechanismofipnsusingsubstrateanalogs
AT hajduj xraystudiesonthemechanismofipnsusingsubstrateanalogs