X-ray studies on the mechanism of IPNS using substrate analogs

X-ray studies on the mechanism of IPNS using substrate analogs

The substrate analog L-S-(a-aminoadipoyl)-L-cysteinyl-glycine (ACG) was co-crystallised with isopenicillin N synthase using the hanging-drop vapourdiffusion method in an anaerobic environment. ' X-ray crystallography revealed a different mode of binding for ACG compared to the natural substrate...

書目詳細資料
Main Authors:	Long, A, Clifton, I, Roach, P, Schofield, C, Baldwin, J, Hajdu, J
格式:	Journal article
語言:	English
出版:	1997

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