Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection.

CD4(+) CD25(+) Foxp3(+) regulatory T (Treg) cells mediate immunological self-tolerance and suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has been reported to enhance the differentiation of Treg cells in the presence of TGF-β. In this study, we show that the co-cul...

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Bibliographic Details
Main Authors:	Moore, C, Tejon, G, Fuentes, C, Hidalgo, Y, Bono, MR, Maldonado, P, Fernandez, R, Wood, K, Fierro, J, Rosemblatt, M, Sauma, D, Bushell, A
Format:	Journal article
Language:	English
Published:	Wiley-VCH 2015

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