Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
BACKGROUND:To deliver efficacious personalised cancer treatment, it is essential to characterise the cellular metabolism as well as the genetic stability of individual tumours. In this study, we describe a new axis between DNA repair and detoxification of aldehyde derivatives with important implicat...
Main Authors: | Chen, X, Legrand, A, Cunniffe, S, Hume, S, Poletto, M, Vaz, B, Ramadan, K, Yao, D, Dianov, G |
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Format: | Journal article |
Language: | English |
Published: |
Springer Verlag
2018
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