Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes.

BACKGROUND: Evidence indicates that myocardial NO production can modulate contractility, but the source of NO remains uncertain. Here, we investigated the role of a type 1 NO synthase isoform (NOS1), which has been recently localized to the cardiac sarcoplasmic reticulum, in the regulation of basal...

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Bibliographic Details
Main Authors: Ashley, E, Sears, C, Bryant, S, Watkins, H, Casadei, B
Format: Journal article
Language:English
Published: 2002