Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
BACKGROUND: MUC2 mucin produced by intestinal goblet cells is the major component of the intestinal mucus barrier. The inflammatory bowel disease ulcerative colitis is characterized by depleted goblet cells and a reduced mucus layer, but the aetiology remains obscure. In this study we used random m...
Main Authors: | Heazlewood, C, Cook, M, Eri, R, Price, G, Tauro, S, Taupin, D, Thornton, D, Png, C, Crockford, T, Cornall, R, Adams, R, Kato, M, Nelms, K, Hong, N, Florin, T, Goodnow, C, McGuckin, M |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2008
|
Similar Items
-
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
by: Heazlewood, C, et al.
Published: (2008) -
Aberrant mucin assembly links endoplasmic reticulum stress with ulcerative colitis
by: Mcguckin, M, et al.
Published: (2007) -
Mucins : methods and protocols /
by: Mcguckin, Michael A., et al.
Published: (c201) -
Endoplasmic reticulum targeting liposomes
by: Pollock, S, et al.
Published: (2011) -
The endoplasmic reticulum stress of placental impoverishment.
by: Redman, C
Published: (2008)