Adult survivors of invasive pneumococcal disease exhibit defective B cell function.

Adults who have recovered from an episode of invasive pneumococcal disease demonstrate defective B cell activation in response to αδ-dex, a polyclonal polysaccharide mimic, compared with matched control subjects. The defect is not overcome by CD4(+) T cell assistance and may explain the relatively p...

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Main Authors: Darton, T, Wing, J, Lees, A, Heath, A, Read, R
格式: Journal article
语言:English
出版: 2011