Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.

BACKGROUND: Integrin-linked kinase (ILK) and its associated complex of proteins are involved in many cellular activation processes, including cell adhesion and integrin signaling. We have previously demonstrated that mice with induced platelet ILK deficiency show reduced platelet activation and aggr...

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Main Authors: Jones, C, Tucker, K, Sasikumar, P, Sage, T, Kaiser, W, Moore, C, Emerson, M, Gibbins, J
格式: Journal article
语言:English
出版: Blackwell Publishing Ltd 2014