Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.
Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved, we have performed a genomewide scan in 185 families containing 255 affected sibling pairs. Two-point a...
Main Authors: | Laval, S, Timms, A, Edwards, S, Bradbury, L, Brophy, S, Milicic, A, Rubin, L, Siminovitch, K, Weeks, D, Calin, A, Wordsworth, B, Brown, M |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2001
|
Similar Items
-
Confirmation of non-MHC genetic loci by whole genome linkage studies in ankylosing spondylitis.
by: Brown, M, et al.
Published: (2000) -
Identification of major loci controlling clinical manifestations of ankylosing spondylitis.
by: Brown, M, et al.
Published: (2003) -
Towards defining the genetic determinants of disease severity in ankylosing spondylitis
by: Brophy, S, et al.
Published: (2001) -
Interleukin-1 and susceptibility to ankylosing spondylitis
by: Edwards, S, et al.
Published: (2001) -
Towards defining the genetic determinants of disease severity in ankylosing spondylitis.
by: Brophy, S, et al.
Published: (2001)