Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.
Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved, we have performed a genomewide scan in 185 families containing 255 affected sibling pairs. Two-point a...
Autori principali: | Laval, S, Timms, A, Edwards, S, Bradbury, L, Brophy, S, Milicic, A, Rubin, L, Siminovitch, K, Weeks, D, Calin, A, Wordsworth, B, Brown, M |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2001
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