Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.

Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved, we have performed a genomewide scan in 185 families containing 255 affected sibling pairs. Two-point a...

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Bibliografiske detaljer
Main Authors: Laval, S, Timms, A, Edwards, S, Bradbury, L, Brophy, S, Milicic, A, Rubin, L, Siminovitch, K, Weeks, D, Calin, A, Wordsworth, B, Brown, M
Format: Journal article
Sprog:English
Udgivet: 2001