A new detergent-free approach to solubilize membrane proteins to maintain their native environment

<p>Biophysical characterisation of membrane receptors in their native environment is essential for drug development, as lipid removal may affect conformational freedom and ligand binding. Membrane proteins are commonly solubilised with detergent for structural and functional studies, althou...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Bada-Juarez, J
مؤلفون آخرون: Watts, A
التنسيق: أطروحة
اللغة:English
منشور في: 2018
الموضوعات: