A new detergent-free approach to solubilize membrane proteins to maintain their native environment

<p>Biophysical characterisation of membrane receptors in their native environment is essential for drug development, as lipid removal may affect conformational freedom and ligand binding. Membrane proteins are commonly solubilised with detergent for structural and functional studies, althou...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Bada-Juarez, J
Άλλοι συγγραφείς: Watts, A
Μορφή: Thesis
Γλώσσα:English
Έκδοση: 2018
Θέματα: