A new detergent-free approach to solubilize membrane proteins to maintain their native environment

<p>Biophysical characterisation of membrane receptors in their native environment is essential for drug development, as lipid removal may affect conformational freedom and ligand binding. Membrane proteins are commonly solubilised with detergent for structural and functional studies, althou...

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Detalhes bibliográficos
Autor principal: Bada-Juarez, J
Outros Autores: Watts, A
Formato: Tese
Idioma:English
Publicado em: 2018
Assuntos: