It takes a PHD to read the histone code.
The pattern of histone modifications, called the histone code, influences transitions between chromatin states and the regulation of transcriptional activity. Four recent papers describe how plant homeodomain (PHD) finger proteins read part of this code. The PHD finger may promote both gene expressi...
| Main Author: | |
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1797072105645277184 |
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| author | Mellor, J |
| author_facet | Mellor, J |
| author_sort | Mellor, J |
| collection | OXFORD |
| description | The pattern of histone modifications, called the histone code, influences transitions between chromatin states and the regulation of transcriptional activity. Four recent papers describe how plant homeodomain (PHD) finger proteins read part of this code. The PHD finger may promote both gene expression and repression through interactions with trimethylated lysine 4 on histone 3 (H3K4), a universal modification at the beginning of active genes. |
| first_indexed | 2024-03-06T23:02:51Z |
| format | Journal article |
| id | oxford-uuid:62c488c1-4795-48ae-865c-822b9f6b503a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:02:51Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:62c488c1-4795-48ae-865c-822b9f6b503a2022-03-26T18:08:22ZIt takes a PHD to read the histone code.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:62c488c1-4795-48ae-865c-822b9f6b503aEnglishSymplectic Elements at Oxford2006Mellor, JThe pattern of histone modifications, called the histone code, influences transitions between chromatin states and the regulation of transcriptional activity. Four recent papers describe how plant homeodomain (PHD) finger proteins read part of this code. The PHD finger may promote both gene expression and repression through interactions with trimethylated lysine 4 on histone 3 (H3K4), a universal modification at the beginning of active genes. |
| spellingShingle | Mellor, J It takes a PHD to read the histone code. |
| title | It takes a PHD to read the histone code. |
| title_full | It takes a PHD to read the histone code. |
| title_fullStr | It takes a PHD to read the histone code. |
| title_full_unstemmed | It takes a PHD to read the histone code. |
| title_short | It takes a PHD to read the histone code. |
| title_sort | it takes a phd to read the histone code |
| work_keys_str_mv | AT mellorj ittakesaphdtoreadthehistonecode |