High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations.

High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations.

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All immunoglobulin G molecules carry N-glycans, which modulate their biological activity. Changes in N-glycosylation of IgG associate with various diseases and affect the activity of therapeutic antibodies and intravenous immunoglobulins. We have developed a novel 96-well protein G monolithic plate...

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Détails bibliographiques
Auteurs principaux: Pucić, M, Knezević, A, Vidic, J, Adamczyk, B, Novokmet, M, Polasek, O, Gornik, O, Supraha-Goreta, S, Wormald, M, Redzić, I, Campbell, H, Wright, A, Hastie, N, Wilson, J, Rudan, I, Wuhrer, M, Rudd, P, Josić, D, Lauc, G
Format: Journal article
Langue:English
Publié: 2011

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