Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56

Checkpoint signaling and error correction require regulation of the MPS1 T-loop by PP2A-B56

During mitosis, the formation of microtubule–kinetochore attachments is monitored by the serine/threonine kinase monopolar spindle 1 (MPS1). MPS1 is recruited to unattached kinetochores where it phosphorylates KNL1, BUB1, and MAD1 to initiate the spindle assembly checkpoint. This arrests the cell cy...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Hayward, D, Bancroft, J, Mangat, D, Alfonso-Pérez, T, Dugdale, S, McCarthy, J, Barr, FA, Gruneberg, U
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Rockefeller University Press 2019

समान संसाधन

CDK1-CCNB1 creates a spindle checkpoint–permissive state by enabling MPS1 kinetochore localization
द्वारा: Hayward, D, और अन्य
प्रकाशित: (2019)

MPS1 localizes to end-on microtubule-attached kinetochores to promote microtubule release
द्वारा: Hayward, D, और अन्य
प्रकाशित: (2022)

PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20
द्वारा: Bancroft, J, और अन्य
प्रकाशित: (2020)

The regulation of Mps1 kinase during mitosis
द्वारा: Mangat, D
प्रकाशित: (2017)

MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling
द्वारा: Alfonso-Pérez, T, और अन्य
प्रकाशित: (2019)

Orchestration of the spindle assembly checkpoint by CDK1‐cyclin B1
द्वारा: Hayward, D, और अन्य
प्रकाशित: (2019)

Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase.
द्वारा: Amy Fabritius, और अन्य
प्रकाशित: (2024-01-01)

Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase
द्वारा: Amy Fabritius, और अन्य
प्रकाशित: (2024-01-01)

Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing
द्वारा: Spyridon T. Pachis, और अन्य
प्रकाशित: (2019-02-01)

Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells
द्वारा: Conrad von Schubert, और अन्य
प्रकाशित: (2015-07-01)

Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing
द्वारा: Margarida Moura, और अन्य
प्रकाशित: (2017-05-01)

Reviews: What does Jeremy think? Jeremy Heywood and the making of modern Britain; Diary of an MP’s wife: Inside and outside power
द्वारा: McCarthy Dermot
प्रकाशित: (2022-05-01)

Chromosomal instability and tumorigenesis : genetic analysis of the murine spindle checkpoint gene Mps1
द्वारा: Xie, Stephanie Zhi-Juan
प्रकाशित: (2007)

The photo-redox of chromium regulated by microplastics (MPs) and MPs-derived dissolved organic matter (MPs-DOM) and the CO2 emission of MPs-DOM
द्वारा: Enyao Zhang, और अन्य
प्रकाशित: (2024-11-01)

A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling
द्वारा: Zhejian Ji, और अन्य
प्रकाशित: (2017-01-01)

Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes.
द्वारा: Nannette Jelluma, और अन्य
प्रकाशित: (2008-01-01)

Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration
द्वारा: Large, E. M., और अन्य
प्रकाशित: (2017)

Obstructive Sleep Apnea in MPS
द्वारा: Abhijit Ricky Pal MBBChir, MA, MD, FRCS(ORL-HNS), और अन्य
प्रकाशित: (2015-11-01)

TTK/MPS1 inhibitor OSU-13 targets the mitotic checkpoint and is a potential therapeutic strategy for myeloma
द्वारा: Larissa Valle Guilhen Longo, और अन्य
प्रकाशित: (2023-07-01)

Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility.
द्वारा: Ricardo Martinez, और अन्य
प्रकाशित: (2015-01-01)

MPS VII – Extending the classical phenotype
द्वारा: A. Oldham, और अन्य
प्रकाशित: (2022-12-01)

Development of a Highly Differentiated Human Primary Proximal Tubule MPS Model (aProximate MPS Flow)
द्वारा: Francesca Pisapia, और अन्य
प्रकाशित: (2023-12-01)

BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment
द्वारा: Luciano Gama Braga, और अन्य
प्रकाशित: (2020-11-01)

Premier listening to chatter on MPs
द्वारा: Goh, Pei Pei
प्रकाशित: (2022)

A Labour MP’s Experience
द्वारा: Peter Kilfoyle
प्रकाशित: (2003-04-01)

Freezing Characteristics of Genetically Modified Lymphocytes for the Treatment of MPS II
द्वारा: A. Hubel Ph.D., और अन्य
प्रकाशित: (1999-09-01)

Reduction of lysosome abundance and GAG accumulation after odiparcil treatment in MPS I and MPS VI models
द्वारा: Pascale Tuyaa-Boustugue, और अन्य
प्रकाशित: (2023-12-01)

MPs-ACT, an Assay to Evaluate the Procoagulant Activity of Microparticles
द्वारा: Yalong Gao PhD, और अन्य
प्रकाशित: (2023-02-01)

10 MPs enrol for postgraduate courses
द्वारा: News Straits, Times
प्रकाशित: (2011)

Building a Bridge to the Future of MPS
द्वारा: Karin Crenshaw
प्रकाशित: (2024-01-01)

Welsh Women MPs: Exploring Their Absence
द्वारा: Sam Blaxland
प्रकाशित: (2020-11-01)

Enzyme replacement reduces neuropathology in MPS IIIA dogs
द्वारा: Allison C. Crawley, और अन्य
प्रकाशित: (2011-08-01)

Critical clinical situations in adult patients with Mucopolysaccharidoses (MPS)
द्वारा: Karolina M. Stepien, और अन्य
प्रकाशित: (2020-05-01)

Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2.
द्वारा: Zeng, K, और अन्य
प्रकाशित: (2010)

Brain pathology in mucopolysaccharidoses (MPS) patients with neurological forms
द्वारा: Viana, GM, और अन्य
प्रकाशित: (2020)

Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression.
द्वारा: Xinghui Wang, और अन्य
प्रकाशित: (2014-01-01)

The multiple roles of mps1 in Drosophila female meiosis.
द्वारा: William D Gilliland, और अन्य
प्रकाशित: (2007-07-01)

Decentralization, Accountability and the 2007 MPs Elections in Kenya.
द्वारा: Gutiérrez-Romero, R
प्रकाशित: (2010)

Decentralization, accountability and the 2007 MPs elections in Kenya
द्वारा: Gutiérrez-Romero, R
प्रकाशित: (2010)

MPS BERJALAN LANCAR DI KAMPUS KEJURUTERAAN
द्वारा: MPRC, Pusat Media & Perhubungan Awam
प्रकाशित: (2016)