Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease
Alzheimer’s disease is characterised by the accumulation and spread of the amyloid beta protein in the brain. Experiments have revealed that amyloid beta oligomers induce microvascular mural cells to contract, thereby constricting capillaries and increasing resistance to blood flow. Conversely, hypo...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Royal Society
2025
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