Hierarchical Bayesian inference for ion channel screening dose-response data

Dose-response (or 'concentration-effect') relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typi...

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Autori principali: Johnstone, R, Bardenet, R, Gavaghan, D, Mirams, G
Natura: Journal article
Lingua:English
Pubblicazione: F1000Research 2016