Hierarchical Bayesian inference for ion channel screening dose-response data

Dose-response (or 'concentration-effect') relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typi...

Повний опис

Бібліографічні деталі
Автори: Johnstone, R, Bardenet, R, Gavaghan, D, Mirams, G
Формат: Journal article
Мова:English
Опубліковано: F1000Research 2016