A nonpeptidic reverse turn that promotes parallel sheet structure stabilized by C-H...O hydrogen bonds in a cyclopropane gamma-peptide.
(Chemical Equation Presented) A twist of fate: Parallel-turn linkers comprising an amino acid derived alcohol conjoined with an aromatic amide through a flexible linkage adopt reverseturn conformations. Cyclopropane tetra-and hexapeptide analogues form a C-H⋯O hydrogen-bond-stabilized parallel-sheet...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2008
|