Genetic risk and resilience for Alzheimer’s disease: The effect of the three APOE alleles on brain function across life

<p>The human apolipoprotein E (APOE) gene has three alleles (ε2, ε3 and ε4). Relative to the most common ε3 allele, ε4 is associated with a higher risk of developing sporadic late-onset Alzheimer’s disease (AD) whereas ε2 is believed to confer a protection to AD. Because of ε4's close ass...

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Bibliographic Details
Main Author: Suri, S
Other Authors: Mackay, C
Format: Thesis
Language:English
Published: 2016
Subjects: