Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered to APCs remains elusive. Since lipoproteins routinely bind...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Engelen, SE, Ververs, FA, Markovska, A, Lagerholm, BC, Kraaijenhof, JM, Yousif, LI, Zurke, Y-X, Gulersonmez, CM, Kooijman, S, Goddard, M, van Eijkeren, RJ, Jervis, PJ, Besra, GS, Haitjema, S, Asselbergs, FW, Kalkhoven, E, Ploegh, HL, Boes, M, Cerundolo, V, Hovingh, GK, Salio, M, Stigter, EC, Rensen, PC, Monaco, C, Schipper, HS
التنسيق:	Journal article
اللغة:	English
منشور في:	American Society for Clinical Investigation 2023

مواد مشابهة

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
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منشور في: (2023-05-01)

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Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
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