Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells
Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered to APCs remains elusive. Since lipoproteins routinely bind...
Auteurs principaux: | Engelen, SE, Ververs, FA, Markovska, A, Lagerholm, BC, Kraaijenhof, JM, Yousif, LI, Zurke, Y-X, Gulersonmez, CM, Kooijman, S, Goddard, M, van Eijkeren, RJ, Jervis, PJ, Besra, GS, Haitjema, S, Asselbergs, FW, Kalkhoven, E, Ploegh, HL, Boes, M, Cerundolo, V, Hovingh, GK, Salio, M, Stigter, EC, Rensen, PC, Monaco, C, Schipper, HS |
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Format: | Journal article |
Langue: | English |
Publié: |
American Society for Clinical Investigation
2023
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