Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low.

The sarcoplasmic reticulum (SR) in ventricular myocytes contains releasable Ca(2+) for activating cellular contraction. Recent measurements of intra-SR (luminal) Ca(2+) suggest a high diffusive Ca(2+)-mobility constant (D(CaSR)). This could help spatially to unify SR Ca(2+)-content ([Ca(2+)](SRT)) a...

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Bibliographic Details
Main Authors: Swietach, P, Spitzer, K, Vaughan-Jones, R
Format: Journal article
Language:English
Published: 2008