G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.

OBJECTIVE: Genetic and environmental factors modulate the susceptibility to diabetic nephropathy, as initiating and/or progression factors. The objective of the European Rational Approach for the Genetics of Diabetic Complications (EURAGEDIC) study is to identify nephropathy susceptibility genes. We...

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Bibliographic Details
Main Authors: Trégouet, D, Groop, P, McGinn, S, Forsblom, C, Hadjadj, S, Marre, M, Parving, H, Tarnow, L, Telgmann, R, Godefroy, T, Nicaud, V, Rousseau, R, Parkkonen, M, Hoverfält, A, Gut, I, Heath, S, Matsuda, F, Cox, R, Kazeem, G, Farrall, M, Gauguier, D, Brand-Herrmann, S, Cambien, F, Lathrop, M, Vionnet, N
Format: Journal article
Language:English
Published: 2008