Subcutaneous adipose tissue from obese and lean adults does not release hepcidin in vivo.
Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue. Obesity is associated with elevated hepcidin concentrations and iron depletion sug...
Main Authors: | Tussing-Humphreys, L, Frayn, K, Smith, SR, Westerman, M, Dennis, A, Nemeth, E, Thomson, J, Pusatcioglu, C |
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Format: | Journal article |
Language: | English |
Published: |
2011
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