Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

Increased circulating plasma urate concentration is associated with an increased risk of coronary heart disease, but the extent of any causative effect of urate on risk of coronary heart disease is still unclear. In this study, we aimed to clarify any causal role of urate on coronary heart disease r...

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Main Authors: White, J, Sofat, R, Hemani, G, Shah, T, Engmann, J, Dale, C, Shah, S, Kruger, F, Giambartolomei, C, Swerdlow, D, Palmer, T, McLachlan, S, Langenberg, C, Zabaneh, D, Lovering, R, Cavadino, A, Jefferis, B, Finan, C, Wong, A, Amuzu, A, Ong, K, Gaunt, T, Warren, H, Davies, T, Drenos, F, Cooper, J, Ebrahim, S, Lawlor, D, Talmud, P, Humphries, S, Power, C, Hypponen, E, Richards, M, Hardy, R, Kuh, D, Wareham, N, Ben-Shlomo, Y, Day, I, Whincup, P, Morris, R, Strachan, M, Price, J, Kumari, M, Kivimaki, M, Plagnol, V, Whittaker, J, Smith, G, Dudbridge, F, Casas, J, Holmes, M, Hingorani, A
Format: Journal article
Language:English
Published: Elsevier 2016

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