Cohesin can remain associated with chromosomes during DNA replication
To ensure disjunction to opposite poles during anaphase, sister chromatids must be held together following DNA replication. This is mediated by cohesin, which is thought to entrap sister DNAs inside a tripartite ring composed of its Smc and kleisin (Scc1) subunits. How such structures are created du...
Main Authors: | Rhodes, J, Haarhuis, J, Grimm, J, Rowland, B, Lavis, L, Nasmyth, K |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
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