Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.

Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset.

The gene encoding insulin receptor substrate-1 (IRS1) represents a strong biological candidate for a contributory role in type 2 diabetes susceptibility. Indeed, functional studies have implicated the G971R variant, and a recent meta-analysis of 27 association studies suggested that carriage of 971R...

Bibliográfalaš dieđut
Váldodahkkit:	Zeggini, E, Parkinson, J, Halford, S, Owen, K, Frayling, T, Walker, M, Hitman, G, Levy, J, Sampson, M, Feskens, E, Hattersley, A, McCarthy, M
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2004

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