A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.

Plasmodium falciparumantigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but their high number and variability provide the pathogen with a powerful means of escape from host antibodies. Although broadly reactive antibodies...

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Hlavní autoři: Tan, J, Pieper, K, Piccoli, L, Abdi, A, Foglierini, M, Geiger, R, Tully, C, Jarrossay, D, Ndungu, F, Wambua, J, Bejon, P, Fregni, C, Fernandez-Rodriguez, B, Barbieri, S, Bianchi, S, Marsh, K, Thathy, V, Corti, D, Sallusto, F, Bull, P, Lanzavecchia, A
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2015

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