Crystal structures of two H-2Db/glycopeptide complexes suggest a molecular basis for CTL cross-reactivity.
Two synthetic O-GlcNAc-bearing peptides that elicit H-2Db-restricted glycopeptide-specific cytotoxic T cells (CTL) have been shown to display nonreciprocal patterns of cross-reactivity. Here, we present the crystal structures of the H-2Db glycopeptide complexes to 2.85 A resolution or better. In bot...
Main Authors: | Glithero, A, Tormo, J, Haurum, J, Arsequell, G, Valencia, G, Edwards, J, Springer, S, Townsend, A, Pao, Y, Wormald, M, Dwek, R, Jones, E, Elliott, T |
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Format: | Journal article |
Language: | English |
Published: |
1999
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