Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression

Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression

عرض إصدارات أخرى (1)

HIF1A is a transcription factor that plays a central role for the adaptation to tissue hypoxia and for the inflammatory response of myeloid cells, including DCs. HIF1A is stabilized by hypoxia but also by TLR ligands under normoxic conditions. The underlying signaling events leading to the accumulat...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Jantsch, J, Wiese, M, Schödel, J, Castiglione, K, Gläsner, J, Kolbe, S, Mole, D, Schleicher, U, Eckardt, K, Hensel, M, Lang, R, Bogdan, C, Schnare, M, Willam, C
التنسيق:	Journal article
اللغة:	English
منشور في:	2011

مواد مشابهة

Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression.
حسب: Jantsch, J, وآخرون
منشور في: (2011)

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing.
حسب: Webb, J, وآخرون
منشور في: (2009)

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
حسب: Mole, D, وآخرون
منشور في: (2009)

Tuning the transcriptional response to hypoxia by inhibiting HIF prolyl- and asparaginyl-hydroxylases
حسب: Chan, M, وآخرون
منشور في: (2016)

HIF-1 and HIF-2: working alone or together in hypoxia?
حسب: Ratcliffe, P
منشور في: (2007)

The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
حسب: Schietke, R, وآخرون
منشور في: (2010)

Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia.
حسب: Johannes Kuhlicke, وآخرون
منشور في: (2007-12-01)

HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia
حسب: Flora Cimmino, وآخرون
منشور في: (2019-02-01)

HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma
حسب: J. Contenti, وآخرون
منشور في: (2024-07-01)

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.
حسب: Pollard, P, وآخرون
منشور في: (2008)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
حسب: Choudhry, H, وآخرون
منشور في: (2014)

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
حسب: Choudhry, H, وآخرون
منشور في: (2013)

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha.
حسب: Elkins, J, وآخرون
منشور في: (2003)

HIF1α stabilization in hypoxia is not oxidant-initiated
حسب: Amit Kumar, وآخرون
منشور في: (2021-10-01)

Signalling hypoxia by HIF hydroxylases.
حسب: Schofield, C, وآخرون
منشور في: (2005)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
حسب: Sowter, H, وآخرون
منشور في: (2003)

Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia
حسب: Fatemeh Sadeghi, وآخرون
منشور في: (2020-06-01)

Hypoxia and HIF pathway in cancer and the placenta
حسب: Macklin, P, وآخرون
منشور في: (2017)

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.
حسب: Morris, MR, وآخرون
منشور في: (2009)

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.
حسب: Raval, R, وآخرون
منشور في: (2005)

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
حسب: Willam, C, وآخرون
منشور في: (2006)

Hypoxia-Inducible Factor-1 (Hif-1) in Experimental Brain Ischemia
حسب: Rainald Schmidt-Kastner, وآخرون
منشور في: (2002-01-01)

Expression of angiogenic factors and hypoxia inducible factors HIF 1, HIF 2 and CA IX in non-Hodgkin's lymphoma.
حسب: Stewart, M, وآخرون
منشور في: (2002)

Inhibition of hypoxia inducible factor (HIF) hydroxylases
حسب: Conejo-Garcia, A, وآخرون
منشور في: (2005)

HIF-1 sensor in detecting hypoxia tolerance at high altitude
حسب: Shaharuddin, Shazreen, وآخرون
منشور في: (2023)

KDM2 Family Members are Regulated by HIF-1 in Hypoxia
حسب: Michael Batie, وآخرون
منشور في: (2017-03-01)

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.
حسب: Dahia, P, وآخرون
منشور في: (2005)

The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability
حسب: Maciej Jaśkiewicz, وآخرون
منشور في: (2022-12-01)

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
حسب: Choudhry, H, وآخرون
منشور في: (2014)

Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.
حسب: Koukourakis, M, وآخرون
منشور في: (2002)

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1(Alpha) (HIF-1(Alpha)).
حسب: Thalhammer, A, وآخرون
منشور في: (2011)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
حسب: Wood, S, وآخرون
منشور في: (1998)

Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo
حسب: Julia Baumann, وآخرون
منشور في: (2022-01-01)

Role of hypoxia-inducible factor-1 (HIF-1) is angiogenesis and tumour biology
حسب: Ratcliffe, P
منشور في: (1999)

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis.
حسب: Carmeliet, P, وآخرون
منشور في: (1998)

Hypoxia/HIF Modulates Immune Responses
حسب: Yuling Chen, وآخرون
منشور في: (2021-03-01)

Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis.
حسب: Muz, B, وآخرون
منشور في: (2009)

Cycling hypoxia selects for constitutive HIF stabilization
حسب: Mariyah Pressley, وآخرون
منشور في: (2021-03-01)

Regulation of angiogenesis by hypoxia: role of the HIF system.
حسب: Pugh, C, وآخرون
منشور في: (2003)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia.
حسب: Hong Lian Li, وآخرون
منشور في: (2017-01-01)