The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells

The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells

The inter-differentiation between cell states promotes cancer cell survival under stress and fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience but its quantification is confounded by genetic heterogeneity. Here we show that NGH in serous ovarian cancer (SOC)...

Descripció completa

Dades bibliogràfiques
Autors principals: Hu, Z, Artibani, M, Alsaadi, A, Wietek, N, Morotti, M, Shi, T, Zhong, Z, Santana Gonzalez, L, El-Sahhar, S, KaramiNejadRanjbar, M, Mallett, G, Feng, Y, Masuda, K, Zheng, Y, Chong, K, Damato, S, Dhar, S, Campo, L, Campanile, R, Soleymani majd, H, Rai, V, Maldonado-Perez, D, Jones, S, Cerundolo, V, Sauka-Spengler, T, Yau, C, Ahmed, AA
Format: Journal article
Idioma:English
Publicat: Cell Press 2020

Ítems similars