Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.

In a previous study we demonstrated that repeated duplications of the tissue kallikrein gene (Klk1) had resulted in 24 paralogs in mouse. Here we demonstrate a different evolution of rat glandular kallikrein genes. Repeated duplications of an approximately 30-kb region, encompassing Klk1, Klk15, and...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Olsson, A, Lilja, H, Lundwall, A
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2004

Παρόμοια τεκμήρια

Expression of prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in ileum and other extraprostatic tissues.
ανά: Olsson, A, κ.ά.
Έκδοση: (2005)

The evolution of the glandular kallikrein locus: identification of orthologs and pseudogenes in the cotton-top tamarin.
ανά: Olsson, A, κ.ά.
Έκδοση: (2004)

Anti-thrombin is expressed in the benign prostatic epithelium and in prostate cancer and is capable of forming complexes with prostate-specific antigen and human glandular kallikrein 2.
ανά: Cao, Y, κ.ά.
Έκδοση: (2002)

Testing in serum for human glandular kallikrein 2, and free and total prostate specific antigen in biannual screening for prostate cancer
ανά: Becker, C, κ.ά.
Έκδοση: (2003)

Testing in serum for human glandular kallikrein 2, and free and total prostate specific antigen in biannual screening for prostate cancer.
ανά: Becker, C, κ.ά.
Έκδοση: (2003)

Association of free-prostate specific antigen subfractions and human glandular kallikrein 2 with volume of benign and malignant prostatic tissue.
ανά: Steuber, T, κ.ά.
Έκδοση: (2005)

Simultaneous quantification of human glandular kallikrein 2 and prostate-specific antigen mRNAs in peripheral blood from prostate cancer patients.
ανά: Ylikoski, A, κ.ά.
Έκδοση: (2001)

Sensitive and specific immunodetection of human glandular kallikrein 2 in serum.
ανά: Becker, C, κ.ά.
Έκδοση: (2000)

Simultaneous quantification of prostate-specific antigen and human glandular kallikrein 2 mRNA in blood samples from patients with prostate cancer and benign disease.
ανά: Ylikoski, A, κ.ά.
Έκδοση: (2002)

Clinical value of human glandular kallikrein 2 and free and total prostate-specific antigen in serum from a population of men with prostate-specific antigen levels 3.0 ng/mL or greater.
ανά: Becker, C, κ.ά.
Έκδοση: (2000)

The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease.
ανά: Becker, C, κ.ά.
Έκδοση: (2001)

Time-resolved fluorescence imaging for specific and quantitative immunodetection of human kallikrein 2 and prostate-specific antigen in prostatic tissue sections.
ανά: Siivola, P, κ.ά.
Έκδοση: (2000)

Intact free prostate-specific antigen and free and total human glandular kallikrein 2. Elimination of assay interference by enzymatic digestion of antibodies to F(ab')2 fragments.
ανά: Väisänen, V, κ.ά.
Έκδοση: (2006)

The role of human glandular kallikrein 2 for prediction of pathologically organ confined prostate cancer.
ανά: Haese, A, κ.ά.
Έκδοση: (2003)

Standardization of two immunoassays for human glandular kallikrein 2.
ανά: Haese, A, κ.ά.
Έκδοση: (2003)

Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade.
ανά: Haese, A, κ.ά.
Έκδοση: (2005)

Biology of prostate-specific antigen
ανά: Lilja, H
Έκδοση: (2003)

Biology of prostate-specific antigen.
ανά: Lilja, H
Έκδοση: (2003)

Rapid elimination by glomerular filtration of free prostate specific antigen and human kallikrein 2 after renal transplantation.
ανά: Bruun, L, κ.ά.
Έκδοση: (2004)

Development of sensitive immunoassays for free and total human glandular kallikrein 2.
ανά: Väisänen, V, κ.ά.
Έκδοση: (2004)

Similar rates of exponential decrease in serum concentrations of free prostate-specific antigen (PSA), PSA complexed to alpha-1-antichymotrypsin, and human glandular kallikrein 2 (hK2) in prostate cancer patients treated with GnRH-analogues.
ανά: Björk, T, κ.ά.
Έκδοση: (2001)

Comparison of free and total forms of serum human kallikrein 2 and prostate-specific antigen for prediction of locally advanced and recurrent prostate cancer.
ανά: Steuber, T, κ.ά.
Έκδοση: (2007)

Risk assessment for biochemical recurrence prior to radical prostatectomy: significant enhancement contributed by human glandular kallikrein 2 (hK2) and free prostate specific antigen (PSA) in men with moderate PSA-elevation in serum.
ανά: Steuber, T, κ.ά.
Έκδοση: (2006)

Evaluation of molecular forms of prostate-specific antigen and human kallikrein 2 in predicting biochemical failure after radical prostatectomy.
ανά: Wenske, S, κ.ά.
Έκδοση: (2009)

Discrimination of men with prostate cancer from those with benign disease by measurements of human glandular kallikrein 2 (HK2) in serum.
ανά: Becker, C, κ.ά.
Έκδοση: (2000)

[Isoforms of free prostate-specific antigen]
ανά: Haese, A, κ.ά.
Έκδοση: (2004)

Isoforms of free prostate-specific antigen
ανά: Haese, A, κ.ά.
Έκδοση: (2004)

Prostate-specific antigen and prostate cancer: prediction, detection and monitoring.
ανά: Lilja, H, κ.ά.
Έκδοση: (2008)

Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer.
ανά: Janssen, S, κ.ά.
Έκδοση: (2004)

Intra-individual short-term variability of prostate-specific antigen and other kallikrein markers in a serial collection of blood from men under evaluation for prostate cancer.
ανά: Christensson, A, κ.ά.
Έκδοση: (2011)

Human glandular kallikrein 2: a potential serum marker for predicting the organ confined versus non-organ confined growth of prostate cancer.
ανά: Haese, A, κ.ά.
Έκδοση: (2000)

Targeting free prostate-specific antigen for in vivo imaging of prostate cancer using a monoclonal antibody specific for unique epitopes accessible on free prostate-specific antigen alone.
ανά: Evans-Axelsson, S, κ.ά.
Έκδοση: (2012)

Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples.
ανά: Végvári, A, κ.ά.
Έκδοση: (2011)

Prostate-specific antigen and related isoforms in the diagnosis and management of prostate cancer.
ανά: Haese, A, κ.ά.
Έκδοση: (2004)

Early prostate-specific antigen changes and the diagnosis and prognosis of prostate cancer.
ανά: Botchorishvili, G, κ.ά.
Έκδοση: (2009)

Prostate kallikrein markers in diagnosis, risk stratification and prognosis.
ανά: Ulmert, D, κ.ά.
Έκδοση: (2009)

Molecular insights into substrate specificity of prostate specific antigen through structural modeling.
ανά: Singh, P, κ.ά.
Έκδοση: (2009)

An empirical evaluation of guidelines on prostate-specific antigen velocity in prostate cancer detection.
ανά: Vickers, A, κ.ά.
Έκδοση: (2011)

Identification of prostate-specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms.
ανά: Végvári, A, κ.ά.
Έκδοση: (2010)

Human glandular kallikrein 2 levels in serum for discrimination of pathologically organ-confined from locally-advanced prostate cancer in total PSA-levels below 10 ng/ml.
ανά: Haese, A, κ.ά.
Έκδοση: (2001)