Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression

The dominant (‘general’) version of the diathesis-stress theory of depression views stressors and genetic vulnerability as independent risks. In the Australian Genetics of Depression Study (N = 14,146; 75% female), we tested whether polygenic scores (PGS) for major depression, bipolar disorder, schi...

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Bibliographic Details
Main Authors: Crouse, JJ, Park, SH, Byrne, EM, Mitchell, BL, Scott, J, Medland, SE, Lin, T, Wray, NR, Martin, NG, Hickie, IB
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2024