Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses.
Polymerase chain reaction for Pneumocystis carinii DNA was performed on necropsy lung samples from children by means of P carinii -specific primers.P carinii DNA was identified in 22 of 22 (100%) samples with histologically proven P carinii pneumonia and 13 of 75 (17%) with non-P carinii pneumonia r...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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| _version_ | 1797072278876323840 |
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| author | Kasolo, F Lishimpi, K Chintu, C Mwaba, P Mudenda, V Maswahu, D Terunuma, H Fletcher, H Nunn, A Lucas, S Zumla, A |
| author_facet | Kasolo, F Lishimpi, K Chintu, C Mwaba, P Mudenda, V Maswahu, D Terunuma, H Fletcher, H Nunn, A Lucas, S Zumla, A |
| author_sort | Kasolo, F |
| collection | OXFORD |
| description | Polymerase chain reaction for Pneumocystis carinii DNA was performed on necropsy lung samples from children by means of P carinii -specific primers.P carinii DNA was identified in 22 of 22 (100%) samples with histologically proven P carinii pneumonia and 13 of 75 (17%) with non-P carinii pneumonia respiratory illness (sensitivity, 100%; specificity, 83%). The low specificity precludes the use of polymerase chain reaction as an alternative to histopathologic diagnosis. |
| first_indexed | 2024-03-06T23:05:28Z |
| format | Journal article |
| id | oxford-uuid:639fc734-3bdb-46e2-86b2-e03ecc2c25bf |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:05:28Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:639fc734-3bdb-46e2-86b2-e03ecc2c25bf2022-03-26T18:14:17ZIdentification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:639fc734-3bdb-46e2-86b2-e03ecc2c25bfEnglishSymplectic Elements at Oxford2002Kasolo, FLishimpi, KChintu, CMwaba, PMudenda, VMaswahu, DTerunuma, HFletcher, HNunn, ALucas, SZumla, APolymerase chain reaction for Pneumocystis carinii DNA was performed on necropsy lung samples from children by means of P carinii -specific primers.P carinii DNA was identified in 22 of 22 (100%) samples with histologically proven P carinii pneumonia and 13 of 75 (17%) with non-P carinii pneumonia respiratory illness (sensitivity, 100%; specificity, 83%). The low specificity precludes the use of polymerase chain reaction as an alternative to histopathologic diagnosis. |
| spellingShingle | Kasolo, F Lishimpi, K Chintu, C Mwaba, P Mudenda, V Maswahu, D Terunuma, H Fletcher, H Nunn, A Lucas, S Zumla, A Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title | Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title_full | Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title_fullStr | Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title_full_unstemmed | Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title_short | Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses. |
| title_sort | identification of pneumocystis carinii dna by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses |
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