Fasting and postprandial hyperghrelinemia in Prader-Willi syndrome is partially explained by hypoinsulinemia, and is not due to peptide YY3-36 deficiency or seen in hypothalamic obesity due to craniopharyngioma.

The cause of the unique elevation in fasting plasma levels of the orexigenic gastric hormone ghrelin in many patients with Prader-Willi syndrome (PWS) is unclear. We measured fasting and postprandial plasma ghrelin in nonobese (n = 16 fasting and n = 8 postprandial) and obese non-PWS adults (n = 16...

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Détails bibliographiques
Auteurs principaux: Goldstone, A, Patterson, M, Kalingag, N, Ghatei, M, Brynes, A, Bloom, SR, Grossman, AB, Korbonits, M
Format: Journal article
Langue:English
Publié: 2005