The tyrosine phosphatase inhibitor vanadate protects osteoblasts from growth inhibition by glucocorticoids.
Príomhchruthaitheoirí: | Hulley, P, Conradie, R, Titus, C, Hough, F |
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Formáid: | Journal article |
Foilsithe / Cruthaithe: |
1999
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Míreanna comhchosúla
Míreanna comhchosúla
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Vanadate protects osteoblasts in vitro and in vivo from glucocorticoid impairment of proliferation
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Pathogenesis of glucocorticoid osteoporosis: Role of tyrosine phosphatases
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Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.
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Glucocorticoid-induced osteoporosis in the rat is prevented by the tyrosine phosphatase inhibitor, sodium orthovanadate.
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Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of osteoblast proliferation.
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