Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast
<p>Chromosomal instability (CIN) drives cell-to-cell heterogeneity, and the development of genetic diseases, including cancer. Impaired homologous recombination (HR) has been implicated as a major driver of CIN, however, the underlying mechanism remains unclear. Using a fission yeast model sys...
| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Oxford University Press
2023
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