Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast

Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast

<p>Chromosomal instability (CIN) drives cell-to-cell heterogeneity, and the development of genetic diseases, including cancer. Impaired homologous recombination (HR) has been implicated as a major driver of CIN, however, the underlying mechanism remains unclear. Using a fission yeast model sys...

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Autors principals:	Pai, C-C, Durley, SC, Cheng, W-C, Chiang, N-Y, Peters, J, Kasparek, T, Blaikley, E, Wee, B-Y, Walker, C, Kearsey, SE, Buffa, F, Murray, JM, Humphrey, TC
Format:	Journal article
Idioma:	English
Publicat:	Oxford University Press 2023

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