Two types of potassium channel regulated by ATP in pancreatic B cells isolated from a type-2 diabetic human.
Two types of K channel regulated by ATP were observed in pancreatic beta cells from a type-2 diabetic man. One type had a conductance of 67 pS at -70 mV in symmetrical 140 mM KCl and was inhibited by intracellular ATP with a half-maximal concentration of 40 microM. ATP inhibition was antagonised by...
Main Authors: | Williams, B, Smith, P, Leow, K, Shimizu, S, Gray, D, Ashcroft, F |
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Format: | Journal article |
Language: | English |
Published: |
1993
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