Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

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Transcriptional interference between adjacent genes has been demonstrated in a variety of biological systems. To study this process in RNA polymerase II (pol II) transcribed genes we have analysed the effect of transcription on tandem HIV-1 promoters integrated into the genome of HeLa cells. We show...

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Bibliographic Details
Main Authors:	Greger, I, Demarchi, F, Giacca, M, Proudfoot, N
Format:	Journal article
Language:	English
Published:	1998

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