Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.
Transcriptional interference between adjacent genes has been demonstrated in a variety of biological systems. To study this process in RNA polymerase II (pol II) transcribed genes we have analysed the effect of transcription on tandem HIV-1 promoters integrated into the genome of HeLa cells. We show...
Autores principales: | , , , |
---|---|
Formato: | Journal article |
Lenguaje: | English |
Publicado: |
1998
|